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diagnosis lupus syndrome sle achalasia capillary cardiomyopathy clarksons comparison dermatology dil disease erythematosus esophageal esophagus gastroenterology hemophagocytic hlh lymphohistiocytosis peripartum
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Disease - Capillary leak ... Relapsing-remitting course +++ Clinical ... Disease #Capillary #leak ... syndrome #diagnosis #management ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... Lupusreference #druginduced ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Drugs, Unknown cause ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... exclude other causes ... Clinical • Under-recognized ... support for patients clinically ... #cardiology #treatment
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment ... #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Xerostomia • Dental caries ... Adenocarcinoma Treatment ... #Diagnosis #Management
Achalasia Summary Epidemiology: 10 cases per 100,000 individuals Defined by inadequate relaxation of the LES and aperistalsis Primary or
Achalasia Summary ... Chagas disease) Clinical ... swallow: • “Bird’s beak ... Three clinical features ... Achalasia #diagnosis #management
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