9 results
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Renal Dosing ... : Apixaban (25% ... renal clearance ... #Pharmacology #Apixaban
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Clotmaster #VTE #DOAC ... #Bridging #Dosing ... Anticoagulation #Dabigatran #Apixaban ... Rivaroxaban #Edoxaban #Loading
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... Hepatic, 0% Renal Apixaban ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... #Pharmacology #Clearance
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... • Apixaban, Dabigatran ... Rivaroxaban • Renal Dosing ... DeLoughery @Bloodman #DOAC ... anticoagulation #CheatSheet #dosing
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... thereby leading ... metabolization leading ... rivaroxaban, and apixaban ... Rivaroxaban and apixaban
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... from warfarin to DOACs ... for easier dosing ... Quick tip: apixaban
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... anticoagulants (DOACs ... recent creatinine clearance ... (calculated using ... inhibitor) • Apixaban
Adult Vancomycin Guidelines
The information below provides general dosing guidelines for vancomycin. A maintenance regimen of 15-20
provides general dosing ... current creatinine clearance ... is the accepted dosing ... AUC: MIC ratio.1 Dosing ... #Loading #Maintenance
Protein Losing Enteropathy
Clinical Presentation:
 • Volume overload: Peripheral edema, pleural effusion or ascites.
 • Gl symptoms
Protein Losing Enteropathy ... -1 antitrypsin clearance ... UTSWIMchief #Protein #Losing