7 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... Anticoagulant Agents Warfarin ... Hepatic, 0% Renal Apixaban ... Hepatic, 35% Renal #DOAC ... #Pharmacology #Clearance
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... : Apixaban (25% ... renal clearance ... Anticoagulation #Hematology ... #Pharmacology #Apixaban
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... to DOACs, or vice ... dosing and monitoring ... Quick tip: apixaban
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Reversal Agents - Warfarin ... (Praxbind) - Apixaban ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Clotmaster #VTE #DOAC ... #Bridging #Dosing ... Anticoagulation #Dabigatran #Apixaban ... #Pharmacology #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... For patients on warfarin ... recent creatinine clearance ... (calculated using ... inhibitor) • Apixaban
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
During the initiation ... diagnosis #models #hematology ... anticoagulant #Warfarin ... thrombin #inhibitor #Apixaban