16 results
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Apixaban (25% renal clearance ... patients 5mg bid Dabigatran ... Anticoagulation #Hematology ... #Rivaroxaban #Dabigatran
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... • Apixaban • Dabigatran ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... Hepatic, 25% Renal Dabigatran ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... #Pharmacology #Clearance
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... VKA, Dabigatran ... Edoxaban, Betrixaban, DOAC ... Anticoagulants #DOACs ... anticoagulation #Switching #hematology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Clotmaster #VTE #DOAC ... #Bridging #Dosing ... Anticoagulation #Dabigatran ... #Pharmacology #Hematology
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... • Apixaban, Dabigatran ... Rivaroxaban • Renal Dosing ... DeLoughery @Bloodman #DOAC ... anticoagulation #CheatSheet #dosing
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Protamine sulfate - Dabigatran ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... from warfarin to DOACs ... for easier dosing ... : apixaban and dabigatran
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... anticoagulants (DOACs ... recent creatinine clearance ... (calculated using ... of Therapy • Dabigatran
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... DOACs are substrates ... metabolization of DOACs ... Dabigatran has moderate ... Chemotherapy #Oncology #Hematology