35 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Malignancy Most common ... ALP elevation DDX ... #Differential #Diagnosis ... #Algorithm #hepatology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... - Most common inherited ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... thrombocythemia), Autoimmune disease ... subsequent enhanced clearance ... #Management #treatment ... #hematology #differential
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
LMWH, warfarin, DOACs ... Advanced Liver Disease ... (VIII is most common ... table #comparison #diagnosis ... #hematology #deficiency
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... cancers: Most common ... DDX - Other causes ... Burns • Protein-losing ... hypogammaglobulinemia #immunology #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... • Most common ... • XR, MRI to dx ... #differential #diagnosis ... #causes #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
uncovered incidentally during ... eosinophilia (common ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
intrinsic lung disease ... • Dyspnea - Common ... ) on room air Treatment ... #management #treatment ... #hepatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Overview: • Most common ... routine CBC (rnost common ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... cells can indicate disease ... Scoring system: DDX ... microglobulin Treatment ... workup #oncology #hematology