16 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... thrombocythemia), Autoimmune disease ... subsequent enhanced clearance ... #Management #treatment ... #hematology #differential
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... late adulthood • Diagnosis ... DDX - Other causes ... Burns • Protein-losing ... hypogammaglobulinemia #immunology #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
intrinsic lung disease ... 80mmHg or A-a gradient ... ) on room air Treatment ... #management #treatment ... #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-1 and IL-6, leading ... kidney failure DDX ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT) - Diagnosis ... , Bivalirudin, DOAC ... re-challenge >100d after Dx ... #Management #Treatment ... #Hematology #HemeOnc
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
over course of disease ... Guidelines recommend using ... Encephalopathy #Grading ... #Management #treatment ... #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... cells can indicate disease ... Scoring system: DDX ... microglobulin Treatment ... workup #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
helmet cells DDX ... • Severe Liver Disease ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
(chronic lung disease ... , left heart disease ... regurgitant velocity using ... pressure < 15mmHg TREATMENT ... #management #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
on bone marrow leading ... extramedullary disease ... plaques) AML Dx ... #Leukemia #Hematology ... #Oncology #Diagnosis