25 results
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... VTE and Renal Dosing ... Renal Dosing ... Apixaban (25% renal clearance ... @Bloodman #DOAC
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... of cancer-associated ... anticoagulants (DOACs ... for appropriate dosing ... #Cancer #Algorithm
Best practice recommendations for the diagnosis and treatment of adult patients experiencing traumatic brain injury during
diagnosis and treatment ... traumatic brain injury during ... treatment with ... Brain #Injury #NOAC ... #DOAC #Management
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... recent creatinine clearance ... (calculated using ... interruption per treatment ... Perioperative #Management #Treatment
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
thrombosis in cancer ... bleeding risk during ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... #Cancer #Algorithm
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... metabolization of DOACs ... concentrations of DOACs
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
adsorption onto cancer ... subsequent enhanced clearance ... Diagnosis #Management #treatment
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... Electrolyte Free Water Clearance ... if you plan on using ... prove feasibility during ... hyponatremia #nephrology #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
B-LNH), solid cancers ... Unknown cause Treatment ... PTLD), allogeneic HSCT ... diagnosis #management #treatment
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Impaired mucociliary clearance ... Diagnosis: • HRCT ... mycobacteria Treatment