14 results
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... ) -> Leg Ulcers, ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis #ExtraArticular
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
Pathogenesis and Clinical ... tightening of skin ... TELANGIECTASIA (In face, hands ... CREST #Syndrome #Pathophysiology ... #Diagnosis #Signs
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease: Clinical ... Edema/erythema on hands ... - Generalized Skin ... #Pathophysiology ... #Vasculitis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... arthralgia, arm/leg ... purpura (lower legs
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... dorsum of the hands ... #Pathophysiology ... #Signs #Symptoms ... #Vasculitis
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
wax and wane; diagnosis ... trauma leads to skin ... painless, no systemic signs ... Sporotrichiosis #Infection #clinical ... #photo #hand
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Abdominal Striae, Thin Skin ... the patient's hand ... Cushings #Syndrome #Signs ... BuffaloHump #Striae #Clinical ... #Photo
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... clumsiness in hands ... saddle anesthesia. leg ... #pathophysiology ... #signs #symptoms
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... Syphilis #Rash #Diagnosis ... #Clinical #Photo
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... = vasculitis vs ... variably: On one hand ... required due to skip