CREST Syndrome: Pathogenesis and Clinical Findings CALCINOSIS (BB-sized, hard nodules in fingers) RAYNAUD'S Phenomenon ESOPHAGEAL DYSMOTILITY SCLERODACTYLY (thickening and tightening of skin distal to MCPs & MTPs) TELANGIECTASIA (In face, hands distal to MCPs and feet distal to MTPs) #CREST #Syndrome #Pathophysiology #Diagnosis #Signs #Symptoms