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diagnosis management differential oncology apml behcet differentiation disease encephalopathy erythematosus lupus monoclonal paraproteinemias posterior pres reversible signs sle systemic vasculitis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... disease (Subcorneal pustular ... (Thrombosis in vascular ... beds-renal, retinal ... Paraproteinemias #Hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... Diagnosis: >3 symptoms ... Differentiation #Syndrome ... diagnosis #management #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... and diplopia) • Vascular ... management #signs #symptoms ... #rheumatology #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Neurological symptoms ... : Acute onset 2 ... , ADEM, Acute toxic ... Seizures: Treat with AEDs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Erythematous, macular ... Pleural effusions • Acute ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... pulse deficits vascular ... affects the skin, neurologic ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
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