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Causes of Depressed / Lethargic Newborn - Differential Diagnosis Algorithm
Maternal Related:
 • Drugs (Ex. SSRI)
 •
Causes of Depressed ... Differential Diagnosis Algorithm ... • Anemia • Shock ... Differential #Diagnosis #Algorithm ... #Causes #Peds #
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Increases BP, SVR, CO ... first agent in shock ... • Higher doses cause ... line in septic shock ... cAMP/cGMP • Causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
anaphylaxis, toxins/meds ... - Low CO and therefore ... - Low CO and therefore ... - Low CO and therefore ... #differential #causes
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Distributive Shock ... Hypovolemic Shock ... differential #diagnosis #algorithm ... #causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
anaphylaxis, toxins/meds ... - Low CO and therefore ... - Low CO and therefore ... - Low CO and therefore ... #differential #causes
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... Framework MAP = CO ... third-spacing • ↓ CO ... findings based on cause ... uw_IMresidency #Shock
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Lactate > 1.5 High CO ... Cord Injury Low CO ... Dehydration Shock ... #criticalcare #algorithm
Shock - Differential Diagnosis Algorithm
Warm Extremities
 - Distributive Shock - Low JVP
Shock - Differential ... Diagnosis Algorithm ... - Distributive Shock ... Differential #Diagnosis #Algorithm ... #causes
Causes of anemia in infants & children

#Diagnosis #Peds #Pediatrics #Differential #Anemia #Causes #Algorithm
Causes of anemia ... #Diagnosis #Peds ... Differential #Anemia #Causes ... #Algorithm
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
: Distributive shock ... ), Cardiogenic shock ... (mild ↑CO) - Side ... , Shock where ↑ ... Bradyarrhythmias, Some cases