4 results
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... #platelet #thrombin ... #clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Coagulation (DIC ... • Increased thrombin ... Reduction of pro/anticoagulants ... INR < 2.3 - APTT ... #diagnosis #causes
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... - Other anticoagulants ... drugs e.g. direct thrombin ... coagulation (DIC ... #Causes #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor and lupus anticoagulant ... Acquired: • Heparin ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... deficiency • Anticoagulant