4 results
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... #platelet #thrombin ... #clot #PT #PTT ... #hematology #pathophysiology ... anticoagulation #anticoagulant
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... Reduction of pro/anticoagulants
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... ABNORMAL PT/ABNORMAL ... deficiency • Anticoagulant
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... - Rivaroxaban, apixaban ... - Other anticoagulants ... coagulation (DIC ... #PT #aPTT #Prolonged