4 results
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... #platelet #thrombin ... #clot #PT #PTT ... #hematology #pathophysiology ... anticoagulation #anticoagulant
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Rivaroxaban, apixaban, edoxaban ... - Other anticoagulants ... inhibitors, heparin ... coagulation (DIC ... #Causes #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
and lupus anticoagulant ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... thrombin inhibitors ... deficiency • Anticoagulant
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants ... INR < 2.3 - APTT