4 results
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#clot #PT #PTT ... #hematology #pathophysiology ... anticoagulation #anticoagulant ... #Warfarin #Dabigatran ... #Edoxaban #heparin
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Coagulation (DIC ... • Prolonged PT ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants ... INR < 2.3 - APTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... , edoxaban (typically ... - Other anticoagulants ... coagulation (DIC ... hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor and lupus anticoagulant ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... deficiency • Anticoagulant ... #Diagnosis #Hematology