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hematology causes abnormal anticoagulation apixaban aptt bleeding bruising dabigatran dic edoxaban hemostasis inhibitor intravascular management models pathway platelet prolonged ptt
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... #clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant ... #Warfarin #Dabigatran
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus anticoagulant ... Acquired: • Heparin ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... deficiency • Anticoagulant
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
- Other anticoagulants ... drugs e.g. direct thrombin ... Disseminated intravascular ... Prolonged #Causes #diagnosis ... #differential #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Increased thrombin ... protein C and S Pathophysiology ... significant fibrin clot ... Reduction of pro/anticoagulants ... #diagnosis #causes
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