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diagnosis hematology causes differential abnormal anticoagulation apaxiban apixaban aptt bleeding bruising coumadin dabigatran dic doac edoxaban hemostasis inhibitor intravascular management
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... and anticoagulants ... #coumadin #heparin ... #warfarin #apaxiban ... #ptt #pt
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... #clot #PT #PTT ... anticoagulation #anticoagulant ... #Warfarin #Dabigatran ... Rivaroxaban #Edoxaban #heparin
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... significant fibrin clot ... Reduction of pro/anticoagulants
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus anticoagulant ... Acquired: • Heparin ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... deficiency • Anticoagulant
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... - Other anticoagulants ... drugs e.g. direct thrombin ... Disseminated intravascular
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