6 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... and Anticoagulant ... #Anticoagulants ... #Medications #Pharmacology ... #Pathophysiology
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
Coagulation Cascade ... K Antagonists: Warfarin ... • Direct Thrombin ... #Cascade #Anticoagulants ... anticoagulation #pharmacology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... clot #PT #PTT #diagnosis ... #models #hematology ... #pathophysiology ... #Warfarin #Dabigatran
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
Review of the Coagulation ... Cascade Traditional ... common pathway): Thrombin ... #Cascade #diagnosis ... #pathophysiology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
, CF, IBD) • Anticoagulant ... Medications - Heparin ... , LMWH, warfarin ... inhibitors, direct thrombin ... table #comparison #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... integrity Clotting cascade ... (warfarin, direct ... thrombin inhibitors