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betadglucan diagnosis galactomannan laboratory infectiousdiseases testing aspergillus beta betad biomarkers characteristics comparison dglucan falsepositives fungi fungus glucan microbiology pathogens specificity
1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics 1,3 ß-D-glucan: • Most fungi excluding mucor and
ß-D-glucan: • Most fungi ... and pneumocystis False ... • False positives ... Characteristics #Sensitivity ... #Fungi #Fungal
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
dermatidis • Sensitivity ... breakthrough IFI in HM • False ... : Mucorales • Sensitivity ... disease - Sensitivity ... recipients, CGD pts • False
(1,3)-β-d-glucan Abundant cell wall polysaccharide, found in most fungi, except cryptococci, zygomycetes (mucor, rhizophus) and blastomyces. Sensitivity 64%-93%;
found in most fungi ... Sensitivity 64%- ... Specificity 87%-100% False ... blood • Certain fungus ... 3)-ß-d-glucan False
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing Sensitivity ... Specificity and False ... component of many fungi ... BAL samples • False ... closely related fungi
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