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diagnosis syndrome symptoms apml arteritis behcet differentiation disease gca giantcell leukostasis lysis oncology temporal tls tumor vasculitis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Rare: DAH, acute ... initiation • Differential ... PE, DAH, CHF, Anaphylaxis ... APML #diagnosis #management ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... WBC >100k, + lab signs ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... thrombosis, VTE) • Cardiac ... Behcet disease) Differential ... #signs #symptoms ... #rheumatology #
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... very remarkable w/differential ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... affects the skin, neurologic ... nose, tracheal collapse ... #Diagnosis #Rheumatology
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