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allergy hematology hypersensitivity management reactions allergic definitions hemeonc hemophagocytic hlh lymphohistiocytosis macrophage pathophysiology rheumatology syndrome table
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antibodies bind to mast ... degranulation of mast ... Complement activation ... #Classification ... Pathophysiology #Allergy #Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... manifestation of MAS ... nervous system (CNS) dysfunction ... Plasma exchange #MAS ... #Syndrome #Diagnosis
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
allergens and activate mast ... degranulation, leading ... because T-Cell activation ... #Classification ... #Diagnosis #Definitions
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... Persistent fever, organ dysfunction ... • In all patients ... Types of HLH • ... (often termed MAS-HLH
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