8 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #HyperKalemia #Nephrology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... #Binders #Management ... #Hyperkalemia #treatment ... #pharmacology #table ... #comparison #nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... also binds magnesium ... of aspiration #Potassium ... #pharmacology #table ... #comparison #binders
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
depletion • Consider K+ ... binder • Consider ... Dialysis Serum potassium ... #hyperkalemia #potassium ... management #algorithm #treatment
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department
 • Place on cardiac
KDIGO Treatment ... depletion • Consider K+ ... binder** • Consider ... #potassium #high ... #nephrology #KDIGO
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Effective arterial volume ... Elimination (see Table ... ) • Optimize volume ... Redistribution Treatments ... #potassium #nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Lactated Ringers ... Saline (NS) - Comparison ... 130 mEq/L • Potassium ... trial • Minimal K ... Normal #Saline #NS #comparison
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Treatment of underlying ... fluid/Lactated ringers ... Monitor potassium ... per day until stable ... #nephrology