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Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... Anemia - Differential ... Antibody/DAT+ - Complement ... Hemolytic #Anemia #Differential ... #Diagnosis #Causes
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
cytokines Common causes ... infection - Allergic ... disease Rare causes ... + T cells) - Allergic ... hypereosinophilia #HE #Differential
NAACP mnemonic for the major causes of Eosinophilia N = Neoplasia (CML, Hodgkins lymphoma) A =
for the major causes ... lymphoma) A = Allergy ... Eosinophilia #NAACP #Differential ... #Causes #Diagnosis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... antigen, leading to complement ... Complement activation ... Pathophysiology #Allergy
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema: • Acute allergic ... exposure • Non-allergic ... cell-mediated in > 90% of cases ... or avoiding the allergen ... Treatment #management #allergy
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... antigens, leading to complement ... they activate complement ... reactions #types #allergy
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis #differential
Drugs Causing Acute Pancreatitis Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... #Pancreatitis #Causes ... #Differential #
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphadenopathy - Differential ... • Acne • Allergy ... Pancytopenia, WBC differential ... Diagnosis #Algorithm #Causes
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