39 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... antigen, leading to complement ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... #Immunology #pathophysiology
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Angioedema: • Acute allergic ... exposure • Non-allergic ... cell-mediated in > 90% of cases ... #Angioedema #Classification
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... Activation of the complement ... #Medication #Causes ... #Pharmacology #Pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... antigens, leading to complement ... they activate complement ... reactions #types #allergy ... #table #classification
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... macrophages, HLA class ... pressure • Tissue edema ... #Rhinorrhea #pathophysiology
Uveitis - Definition, Causes and SUN Classification

Inflammation of the iris, ciliary body, vitreous, retina and/or choroid
Incidence
- Definition, Causes ... and SUN Classification ... linked to macular edema ... Bartonella SUN Classification ... #SUN #Classification
Peripheral Edema - Differential Diagnosis Framework for Lower Extremity Edema

Edema occurs when any of the following
Peripheral Edema ... Edema occurs ... Non-pitting) • Allergic ... iliac vein which crosses ... #PhysicalExam #Pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... Idiopathic • Normal Complement
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm
INDICATIONS FOR TESTING:
 • Recurrent angioedema (without urticaria)
 •
Complement 1 esterase ...  • Laryngeal edema ... ARUPLabs #C1INH #Complement ... Testing #Algorithm #allergy