9 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... antigen, leading to complement ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
Septic shock ... with Shock: Sepsis ... NETs), cytokines, complement ... • Symptoms: Fever ... #Septic #Shock
Decision tree of FALLS-protocol (Fluid Administration Limited by Lung Sonography). Lung Ultrasound in the hemodynamic assessment
assessment of Shock ... According to Weil classification ... , i.e. septic shock ... FALLS #protocol #algorithm ... #CriticalCare #Shock
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Anaphylaxis, Hay fever ... antigens, leading to complement ... they activate complement ... reactions #types #allergy ... #table #classification
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
of Acute Onset Fever ... Differential Diagnosis Algorithm ... Continuous Bacteremia Septic ... Shock Acute Organ ... Differential #Diagnosis #Algorithm
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... • Bacteremia/Septic ... Shock • Encapsulated ... Periodontal Disease Complement ... Infection #Fever
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
pharyngeal erythema, fever ... pharyngeal erythema, fever ... , altered LOC; septic ... rash; symptoms of shock ... peds #pediatrics #pathophysiology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
tachycardia or fever ... hypotension or septic ... shock, 33% had ... CBC #hematology #pathophysiology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
respiratory symptoms • Fever ... Aspergillosis Pathophysiology ... • Isolated fever ... • Septic shock ... • Meningitis, septic