30 results
diagnosis differential rheumatology hypersensitivity management nephrology allergy reactions table comparison pathophysiology pulmonary renal shock allergic cold criticalcare definitions disease fractures
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... Post-streptococcal glomerulonephritis ... #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... Skin ulcers - Glomerulonephritis ... Types: • Type ... • Low serum C4 complement ... #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive Glomerulonephritis ... staining): • Low Complement ... Idiopathic • Normal Complement ... Kidney: Anti-GBM Glomerulonephritis ... #Vasculitis #differential
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
cell antigens, leading ... to complement activation ... they activate complement ... Post-streptococcal glomerulonephritis ... allergy #table #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Necrotizing glomerulonephritis ... , pauci-immune glomerulonephritis ... • Glomerulonephritis ... against MPO • Complement ... #rheumatology #classification
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
rapidly progressive glomerulonephritis ... ANCA Associated Vasculitis ... anti-GBM) 10%: - Low Complement ... - Normal Complement ... Renal Crisis, IgA Vasculitis
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Membranoproliferative glomerulonephritis ... , type 1 (50%-80% ... ), type II (80-90% ... Post/pauci immune glomerulonephritis ... Hypocomplementemia #Low #Complement
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Vasculitis - Break ... by large vessel vasculitis ... medium vessel vasculitis ... can affect any type ... Medium #Large #Classification
Salter-Harris Classification Salter-Harris Fractures involve the physis and cartilaginous epiphyseal plate near the ends of the long
Salter-Harris Classification ... bones in still growing ... Salter-Harris fracture types ... SalterHarris #Fractures #Classification ... #Types #SALTR #
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Graves' Disease Type ... Post-infectious glomerulonephritis ... #Classification
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