33 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... antigen, leading to complement ... Complement activation ... Classification #Pathophysiology ... #Allergy #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
Leishmaniasis #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Echinococcus Life Cycle
1) Adult in small intestine eggs
2) Embryonated egg in feces
3) Oncosphere hatches; penetrates intestinal
#Echinococcus #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Strongyloides fuelleborni Lifecycle
Free-Living Cycle
1) Eggs containing rhabditiform larvae passed in feces.
2) Rhabditiform larvae hatch in environment.
Strongyloides fuelleborni Lifecycle ... #fuelleborni #LifeCycle ... Parasite #diagnosis #pathophysiology ... #infectiousdiseases
Malaria - Plasmodium Life Cycle
1) Mosquito takes a blood meal (injects sporozoites)
Human Liver Stages
2) Infected liver
Malaria #Plasmodium #lifecycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Echinostomiasis - Echinostoma Life Cycle
1) Unembroynated eggs passed in feces
2) Embryonated eggs in water
3) Miracidia hatch
#Echinostoma #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Babesiosis - Babesia Life Cycle
1) Tick takes a blood meal (sporozoites introduced into host)
2) Trophozie ←→
Babesiosis #Babesia #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
activates the complement ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Amebiasis - Balamuthia mandrillaris Life Cycle
1) Cysts
2) Trophozoite
3) Mitosis
4) Amebae (cysts and trophozoites) can enter humans
who are immune competent ... #mandrillaris #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases