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diagnosis differential neurology algorithm management aki glomerulonephritis kidney rheumatology acute classification comparison injury pathophysiology renal workup clinical nephrotic testing treatment
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... staining (lg + complement ... MGPN • Complement ... of alternative complement ... Glomerulonephritis #MPGN #nephrology
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... spondyloarthropathies, vasculitides ... See below for table ... helpful paper complements ... #Differential #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... When to Consider Vasculitis ... SMALL VESSEL VASCULITIS ... tract, and often causes ... against MPO • Complement
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... • IgA vasculitis ... • Vasculitis
Causes of Peripheral Weakness with Sensory Changes - Differential Diagnosis Algorithm Radiculopathy: • Disc • Spondylosis •
Causes of Peripheral ... Multiplex: • Vasculitis ... Weakness #Sensory #Neurology ... Diagnosis #Algorithm #Causes
Unmeasured Anions Associated with an Elevated Anion Gap and Metabolic Acidosis #Unmeasured #Anions #Gap #Metabolic #Acidosis #Diagnosis
Acidosis #Diagnosis #Nephrology ... #Table #Differential ... #Causes
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... Activation of complement ... Leukocytoclastic vasculitis ... periumbilical region), nausea ... #HSP #IgA #Vasculitis
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... malformation, Aneurysm, Vasculitis ... Diagnosis #Algorithm #Causes ... #neurology
Reversible Neurocognitive Disorders (Reversible Causes of "Dementia") • Structural/Mass: Subdural Hematoma, NPH, Intracranial tumor • Infection:
Disorders (Reversible Causes ... , Sleep apnea, Vasculitis ... differential #diagnosis #causes ... #neurology
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