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diagnosis differential management rheumatology types cardiology hypersensitivity neurology reactions immunology peds signs symptoms treatment allergic dermatology hematology hypersensitivityreaction nephrology pediatrics
Allergic Reaction Classification Type 1 reaction: Acute anaphylactic reaction Type 2 reaction: Cytotoxic reaction Type 3 reaction: Immune complex Type
Allergic Reaction ... Classification ... reaction: Immune complex ... #Reaction #Classification ... #Types #allergy
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... complex -> Allergen-antibody ... complexes bind ... #Immunology #pathophysiology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... antibiody -> Immune Complex ... > Incr Immune Complex ... Formation -> Vasculitis ... #HUV #Pathophysiology
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Antigen-Ab immune complexes ... #Allergic #Reactions ... #Types #Classification
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
cell surfaces causes ... antigen-surface complex ... antibody-antigen complexes ... causes development ... #Types #Classification
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
antigen-surface complex ... antigen-surface complex ... against these complexes ... or the entire complex ... #Immunology #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
antigen-antibody complexes ... self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Vasculitis - Break ... by large vessel vasculitis ... medium vessel vasculitis ... although immune complex ... Medium #Large #Classification
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... Differential Diagnosis Algorithm ... Focal: Simple, Complex ... malformation, Aneurysm, Vasculitis ... #Causes #neurology
Causes of Tachycardia - Differential Diagnosis Algorithm Narrow Complex - Regular: • Sinus tachycardia • Atrial flutter
Narrow Complex ... tachycardia Narrow Complex ... conduction Wide-Complex ... Pacemaker-facilitated Wide-Complex ... aberrancy Wide-Complex
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