48 results
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen Pathophysiology ... Lipopolysaccharide components ... stranded RNA • Fungi ... Mannan and glucan components ... vasculature via: • Active
Patterns of Diseases on MRI FLAIR - Differential Diagnosis
ADEM, Adreno-leukodystrophy, CADASIL, CNS, Lymphoma, High-Grade Glioma, HIV
Patterns of Diseases ... - Differential Diagnosis ... : Active, MS: Inactive ... Vessel Ischemic Disease ... #Differential #Diagnosis
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... smoking, etoh, decr activity ... #Osteoporosis #pathophysiology ... signs #symptoms #diagnosis
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... Double-stranded RNA • Fungi ... Mannan and glucan components ... vasculature via: • Active ... InfectiousDiseases #Diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... Mycobacterial • Fungal ... tuberculosis) • Fungi ... #Differential #Diagnosis ... #MSK #rheumatology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... colonization vs invasive disease ... admin of mold-active ... Galactomannan #diagnosis
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... description: • Active ... exacerbated with activity ... clinical #Radiology #diagnosis ... #msk
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... in macrophages Diagnosis ... ß-glucocerebrosidase activity ... #Diagnosis #Signs
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Chronic kidney disease ... infection (NTM) • Fungal ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis
Infectious Joint Pain - Differential Diagnosis Algorithm 
Polyarticular Join Pain
 • Viral Myalgia
 • Viral Arthritis
- Differential Diagnosis ... Lesions) • Fifth Disease ... Onset • Fungal ... Infectious #JointPain #MSK ... #Differential #Diagnosis