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Initial Clinical and Laboratory Data Base for Defining Major Syndromes in Nephrology

#Major #Syndromes #Nephrology #Diagnosis #Workup
Defining Major Syndromes ... in Nephrology ... #Major #Syndromes ... #Workup #Differential ... #Table
Pocket Comparison Guide to Heritable Hypertension Syndromes (Secondary Hypertension)

Bartter, Gitelman, Liddle, Primary Aldosteronism, 
GRA (Glucocorticoid Remediable
Heritable Hypertension Syndromes ... Geller (Activating MR ... #Hypertension #Syndromes ... #Comparison #Table ... #Diagnosis #Management
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
Hypertension - Differential ... CT or MRI scan of ... • Cushing’s syndrome ... #Hypertension #Differential ... Screening #Workup #table
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
MRI, iADL scale, ... Aphaso-apraxo-agnosia syndrome ... - 25% genetic component ... MNCD #Dementia #Differential
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... Testing #Causes #differential ... #diagnosis #table ... #neurology
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Irritable bowel syndrome ... barium, CT, or MR ... Malabsorption syndromes ... Chronic #Diarrhea #management ... workup #diagnosis #differential
Hypermagnesemia - Etiologies by Mechanism
Renal Failure 
Excessive Mg Administration 
 - Massive PO intake
- Tumor lysis syndrome ... Hypermagnesemia #Differential ... High #Magnesium #Table ... #Causes #Management
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
limb Gitelman syndrome ... tubule Liddle syndrome ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... + MRI lesions + ... Lesions #Brain #differential ... causes #radiology #neurology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
BEE Syndromes - ... recessive—Usher syndrome ... neuropathy (LHON) plus MRI ... #neurology #noninflammatory ... #differential #