12 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... delivery to distal nephron ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... loop and distal component ... of Nephron: CHF ... absorption in distal nephron ... KidneyDisease #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Differential Diagnosis ... - Bartter - Gitelman ... Cl⁻ with other components ... #Algorithm #Pathophysiology ... #Nephrology #Chloride
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
and lower motor neuron ... Injury #Syndromes #diagnosis ... #pathophysiology ... #orthopedics #neurology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
peripheral nerve components ... bulbar muscles DIAGNOSIS ... the underlying pathophysiology ... Barre #Syndrome #diagnosis ... #management #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Monoclonal Protein/M Component ... et diutinum Neurologic ... myeloma↑VEGF+M component ... Hypergammaglobulinemic macular ... #Differential #Diagnosis
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Mutism Pathophysiology ... • Vestibulo-ocular ... #PhysicalExam #neurology ... #comatose #diagnosis
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Histoplasmosis Diagnosis ... by culture or serology ... Aspergillosis Pathophysiology ... osteoarticular, pulmonary, ocular ... : • Serology for