9 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... Proximal tubule Bartter ... #Nephron #Defects ... #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Extra-renal Losses ... thiazide diuretics, Bartter ... syndrome, Gitelman
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Diagnosis Algorithm ... - Diuresis - Bartter ... - Gitelman ... Cl⁻ with other components ... #Pathophysiology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Hypokalemia - Differential ... Diagnosis Algorithm ... • Diuretics, Bartter's ... syndrome, Gitelman's ... #causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
• Hypokalemia (renal ... ratio 0.5%) Differential ... Sjögren syndrome, Renal ... syndrome • Pseudo Bartter-Gitelman ... #management #pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... suggests extra-renal ... Emesis, Diuretics, Bartter ... syndrome, Gitelman ... #differential #
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes