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diagnosis hematology risk stratification antibiotics disease febrile hemophagocytic hlh infant lp lymphohistiocytosis oncology pediatrics perioperative stepbystep activation anemia anesthesia anesthesiology
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... for each of the components ... of the algorithm ... #Diagnosis #Management ... #Pediatrics #Peds
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Diagnosis and Treatment ... Algorithm Matthew ... #HES #Hematology ... eosinophils #diagnosis #management ... #algorithm
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... : • Treatment: ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology #rheumatology
Checklist for Treatment of Delirium in the ICU Remove causative factors - Exclude hypoglycemia if
Checklist for Treatment ... c deliriogenic meds ... or persistent fevers ... #Delirium #Checklist ... #Management #Treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... - Nonremitting fever ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... Actively maintained fever ... • Serotonin syndrome ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... TLS #diagnosis #management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... following: • Fever ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
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