9 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Highest • Bone • Liver ... - Fatigue - Pruritis ... - Drugs - Primary ... #hepatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Differential Diagnosis Algorithm ... • Cholestatic liver ... renal failure/uremia ... #primary #secondary
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Symptoms: Fatigue, Pruritus ... Elevated ALP 2. ... Liver biopsy findings ... #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... pain • loss of secondary ... • Pernicious anemia ... • Elevation of urinary ... Hyophosphatasia #hepatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... • Cholestatic liver ... renal failure/uremia ... #secondary #systemic ... #generalized #dermatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... urgent referral to secondary ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... #Hepatology #Liver
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... asymptomatic • Pruritus ... PBC Labs: • Alkaline ... obstruction • ALP ... or higher • Liver
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
with no primary ... • Liver disease ... • Hematologic ... #Treatment #Algorithm ... #Management #Nephrology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... - infiltrates (anemia ... + distinctive primary ... bone marrow and secondary ... #Leukemia #Hematology