10 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Liver ... renal failure • Uremia ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
to Anemia - Differential ... Sideroblastic anemia ... ACD, Aplastic anemia ... , CKD • Hemolytic ... MatthewHoMD #Anemia
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... Diabetes Mellitus Liver ... • Cholestatic liver ... renal failure/uremia ... Pruritus #primary #secondary
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
• Cholestatic liver ... renal failure/uremia ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... Thrombocytopenia: ITP • Secondary ... - Hemolytic anemia ... Splenomegaly - CTD ... deficiency • Liver
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... with leukopenia, anemia ... thrombocytopenia • Liver ... Diagnosis #Management #Hematology ... #Rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... disease • Liver ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... hypogammaglobulinemia #immunology #hematology
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
pruritus • Liver ... pruritus • Hematologic ... Iron deficiency anemia ... #Uremia #Management ... #Nephrology #CKD
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
function of multiple systems ... embolism - Severe anemia ... Auditory/Vestibular System ... neglect, postictal confusion ... #Neurology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... STX11, STXBP2 • Secondary ... - Cytopenias (anemia ... - Elevated liver ... Diagnosis #Management #Hematology