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diagnosis management hemophagocytic lymphohistiocytosis rheumatology hemeonc macrophage mas summary syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... adenopathies, confusion ... B-LNH), solid cancers ... Unknown cause Treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... lymphohistiocytosis (HLH ... thrombocytopenia • Liver ... 10,000 ng/mL • Hyponatremia ... Treatment: • Corticosteroids
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
by uncontrolled activation ... it is often a cancer ... - Elevated liver ... Treatment Approach ... Diagnosis #Management #Hematology
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