16 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium-Binding Agents ... Potassium #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding Agents ... to Treat Hyperkalemia ... Potassium #Binding #Hyperkalemia ... #pharmacology #table ... #comparison #binders
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Lower risk of hypercalcemia ... range - Lack of hypercalcemia ... requirements - Lack of hypercalcemia ... range - Lack of hypercalcemia ... #Table #Comparison
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... phosphate binding agents ... since they are not able ... aluminum-based phosphate binder ... restricted due to hypercalcemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
• LDH ↑ • Hyperkalemia ... /Late - Hypercalcemia ... fluid/Lactated ringers ... per day until stable ... Dialysis for severe hyperkalemia
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV ... • Consider K+ binder ... , asystole #hyperkalemia ... #treatment
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Acute and Chronic Hyperkalemia ... Acute Hyperkalemia ... Chronic Hyperkalemia ... optimization) #Hyperkalemia ... Acute #Chronic #treatment
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
of Hyperkalemia ... redistributive hyperkalemia ... on ECG, severe hyperkalemia ... Figure 3 is an algorithm ... , and Table 3 summarizes
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... removal of offending agent ... not quickly) #Hyperkalemia ... #Treatment #Algorithm