17 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Lupus (DIL): ... cases, drug-dependent ... #table #rheumatology ... #diagnosis #management
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... cases, drug-dependent ... #Lupus #DIL #rheumatology ... #diagnosis #treatment ... #management
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... duration), Several medications ... /HDS treatments ... for alternative causes ... #DrugInduced #Liver
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... of SLE versus DIL ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
: Drugs: Ecstasy ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... Hyperthermia #comparison #diagnosis ... #management #treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... and Management ... Drugs (Statins), ... if levels > 8mg/dL ... #causes #treatment
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... anaphylaxis (→ 3-1) Drug ... #Differential #Causes ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Framework and Management ... Summary Causes ... - Toxins - Drugs ... #Management #causes
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
immediately. ❼ Give drugs ... as patient is stable ... annotate notes/drug ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
source of energy, conversion ... circulation If drugs ... before beginning treatment ... - Compartment syndrome ... - HIV/HAART medications