7 results
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Start with initial dose ... daily • Adjust dose ... Increase dose gradually ... highest dose tolerable ... #Pharmacology #
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Antihypertensive Dose ... for better pre-dose ... potassium, and renal ... ACEInhibitor #ACEIs #Dosing ... #Conversion #Pharmacology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
on the highest dose ... only use lower doses ... at the lowest dose ... make sure the dose ... #Dosing #Pharmacology
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
first-line medication ... titrating the dose ... until at optimal dose ... attention to patients renal ... #Pharmacology #
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Calculate total daily dose ... Adjust insulin dose ... for renal dysfunction ... #pharmacology # ... comparison #table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
10 g QD (adjust dose ... Usual maintenance dose ... g QD; increase dose ... #pharmacology # ... table #comparison
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
Renal Replacement ... Pager Summary Indications ... carbamazepine, metformin ... clearance and does ... dialysate flow (both convection