23 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Trauma, Tumor • Motor ... Poliomyelitis, Guillain-Barre ... #differential #diagnosis ... #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... Pathophysiology ... Diagnosis: • ... #diagnosis #management
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Criteria for Guillain ... sensory symptoms or signs ... , Cranial nerve ... nervous system signs ... #neurology #neuropathy
Upper Extremity Dermatomes and Myotomes
Motor Function
Shoulder:
 • Abduction - C5,C6 (axillary)
 • Adduction - C6, C7,
and Myotomes Motor ... Carpal Tunnel Syndrome ... Dermatomes #Myotomes #diagnosis ... #neurology #sensory ... #motor #arm #physicalexam
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Complete loss of motor ... upper and lower motor ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
• Cauda Equina Syndrome ... Commonly caused ... damage to peroneal nerve ... Dermatomes #Myotomes #diagnosis ... #motor #leg #physicalexam
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
Causes of Hemiplegia ... - Differential Diagnosis ... (Contralateral motor ... Consciousness • Cranial Nerve ... Brown-Sequard Syndrome
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... concentration • Motor ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... the underlying pathophysiology ... #Barre #Syndrome ... #neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... damage to sacral nerves ... #MSK #pathophysiology ... #diagnosis #symptoms