17 results
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Contact lens use • Eye ... Bilateral, asymmetric corneal ... Signs / Symptoms ... • Corneal Opacities ... #pathophysiology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
production -> Corneal ... • Loss of the eye ... non-functional eye ... #Xeropthalmia #pathophysiology ... ophthalmology #diagnosis #signs
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
all coats of the eye ... interior of the eye ... Exposes cornea -> Corneal ... Orbital #Cellulitis #pathophysiology ... ophthalmology #diagnosis #signs
Trachoma: Pathogenesis and clinical findings

 • Environmental Factors -> Bacterial infection is encouraged by poor hygiene
Transmission -> Eye-seeking ... fibrosis => • Corneal ... Lubrication • Dry eye ... Trachoma #Chlamydia #pathophysiology
Onchocerciasis “River Blindness”: Pathogenesis and Ocular Manifestations
Vectorial Transmission
-> Onchocerca volvulus, a parasitic helminth, matures in to
Microfilariae enter the eye ... stromal keratitis -> Corneal ... RiverBlindness #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... detachment • Red Eye ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis #signs
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Blood: Anemia Eyes ... Episcleritis) -> Sudden eye ... glands -> Dry Eyes ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Interstitial keratitis in Tertiary Syphilis

Interstitial keratitis, which is an inflammation of the cornea’s connective tissue elements,
inflammation of the cornea ... usually affects both eyes ... though there are no signs ... brain, nerves, eyes
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
present with a red eye ... Occurs in small eyes ... damage & blindness Signs ... obstruction • Corneal ... ClosedAngle #Glaucoma #pathophysiology
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Note: Eye exam ... If the eye cannot ... Periorbital #Cellulitis #pathophysiology ... ophthalmology #diagnosis #signs