8 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... Diagnosis should be based ... Suspect in movement disorders ... sensitivity of serum CrAg ... #diagnosis #AIDS
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Zone Lymphoma (HCV ... WAIHA • CAD • PCH ... ↓anion gap • CRAB ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Cold Agglutinin Syndrome ... Mycoplasma, EBV, HIV ... younger pts) Differential ... hemolytic #anemia #hematology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... (AG) = {Na - (Cl ... glycol (present in IV ... D-lactate (short bowel syndrome ... bloodgas #Acid #Base
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... HoTN, edema and effusions ... initiation • Differential ... • Steroids: IV ... diagnosis #management #hematology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
- Differential ... Pneumonia: • 3 syndromes ... pneumonia, pleural effusion ... #AIDS #pulmonary ... #differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... Lungs: • Pleural effusions ... vein thrombosis Hematologic ... La, anti-Jo-1, SCL
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... /AIDS patients ... be present: • AIDS ... infiltrates, pleural effusions ... #Differential #