5 results
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
WAIHA • CAD • PCH ... Evans • ITP • Cl-NH ... ↓anion gap • CRAB ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
HoTN, edema and effusions ... initiation • Differential ... fluid overload, PCC ... diagnosis #management #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... importantly, bedside ultrasound ... Adequate perfusion ... #diagnosis #differential ... heartfailure #chf #criticalcare
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... Lungs: • Pleural effusions ... vein thrombosis Hematologic ... La, anti-Jo-1, SCL
Severe Influenza Checklist

Diagnostic tests 
 - Blood cultures x2 
 - Sputum gram stain & culture
antigens - Nares PCR ... function tests - Ultrasound ... needed to exclude effusion ... Checklist #Management #CriticalCare