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differential renal scleroderma signs chest clinical management miliary nephrology pathophysiology pattern prs rheumatology ssc syndrome syndromes systemic systemicsclerosis testing treatment
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
thickening, distal to elbows ... and knees • Diffuse ... (DcSSc; diffuse ... : ILD (interstitial ... #rheumatology #diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Definition: Diffuse ... Differential Diagnosis ... arthritis, Systemic sclerosis ... , anti-CCP • CXR ... resolution chest CT
Miliary Pattern - Chest Radiology • Miliary opacities are scattered, small (1 -4 mm) nodules •
Pattern - Chest Radiology ... mm) nodules • Diffusely ... Differential Diagnosis ... #pulmonary #CXR ... #clinical #CT
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Inflammatory eye disease: scleritis ... Other tests: • CT ... or serologies + symptoms ... hemorrhage (DAH) • Diffuse ... seen on chest CT
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
Sclerosis (Scleroderma ... Crackles, Abnormal CXR ... - Finger/hand/elbow ... pathophysiology #signs #symptoms ... #diagnosis
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