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diagnosis management cardiology mri algorithm c5c9deficiency cardiomyopathy complement crypto cryptococcal differential fatigue heartfailure hfref immunology iron leigh myelitis neurology pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
Pathogenesis and Clinical ... • Bacteria cross ... the blood-brain ... swelling and damaging brain ... Inflammation of CSF
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Fatigue and IBD ... fatigue despite clinical ... UC Anemia and IBD ... IDA and active IBD ... /other causes •
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... → Inflammation causes ... ng/mL (absolute ID ... 20% (functional ID ... #CHF #HFrEF #heartfailure
Leigh Syndrome History: 19-month-old girl with hypotonia, developmental delay, failure to thrive, and bilateral optic disc
History: 19-month-old ... was a complex I deficiency ... Leigh #Syndrome #Clinical ... #MRI #Brain #Diagnosis ... #Radiology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... than 2/3 of the cross-sectional ... • Infectious causes ... ruled out • Brain ... • Nutritional Deficiency
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Clinical • Under-recognized ... May have typical HF ... Avoid ARBs • ICD ... support for patients clinically
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Cryptococcal meningitis ... Nausea & vomiting ... )but severe K+ deficiency ... #T2 #MRI #Brain ... #clinical #radiology
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