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diagnosis rheumatology differential antinxp2 antinxp2dm clinical coagulation comparison deficiencies dermatomyositis distribution drugrelated erythematosus exanthema flexural intertriginous lupus management myopathy myositis
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
celiac disease, CF, IBD ... Viral hepatitis, Autoimmune ... (VIII is most common ... - Malignancy, Autoimmune ... comparison #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
disease • Non-autoimmune ... disease • Prolidase deficiency ... deficiencies • Autoimmune ... CNS • Headache, mild ... Kidney disease common
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 49M +burning rash groins/buttocks (pic in next thread) x 1d.
groins/buttocks ... warm,red patch groins ... MCQ highlights a case ... Washington University ID ... clinical #photo #dermatology
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
Common Dermatological ... • Psoriasis - Elbows ... Lesions arise in crops ... ; pruritis #dermatology ... #rash #differential
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... Muscle atrophy may cause ... Dermatomyositis: • ILD ... #dermatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Inflammatory Myopathies: Commonly ... Anti-MDA5 (RP-ILD ... Symptoms: • Gottron rash ... statins - probably caused ... Myositis #Myopathy #rheumatology
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