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hematology reactions antibiotics blood fever infant lp peds product risk stepbystep stratification syndrome transfusion apml complications differentiation ebm hemophagocytic hlh
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... components of the algorithm ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Rare: DAH, acute ... febrile neutrophilic ... Renal Failure Treatment ... #management #hematology
Transfusion Reactions - Summary Cheatsheet • Hemolytic Reaction • Febrile Reactions • Transfusion Related Acute Lung
Hemolytic Reaction • Febrile ... Transfusion Related Acute ... Lung Injury (TRALI ... Transfusion #Reactions #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presents as an acute ... or subacute febrile ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... organ damage • Treatment ... : - If febrile ... Syndrome #TLS #diagnosis ... #management #hematology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Mediated: • Febrile ... • Acute Hemolytic ... Lung Injury (TRALI ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Mediated: - Febrile ... - Acute Hemolytic ... Lung Injury (TRALI ... #Transfusions #diagnosis ... #management #hematology
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