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diagnosis management hematology differential infections leukemia rheumatology infectiousdiseases abscess acute amyloid amyloidosis band cirrhosis classification clinical common cvid dermatology encephalopathy
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cells can indicate disease ... microglobulin Treatment ... #Chronic #Lymphocytic ... diagnosis #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... • Tumor lysis syndrome ... (Chronic Lymphocytic ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Vmphocytosis on routine CBC ... chemotherapy for low-risk disease ... #Chronic #Lymphocytic ... #Leukemia #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Cr >2 mg/dL or CC ... Causes of false- ... diseases, CML, ... plasmacytoma, POEMs syndrome ... diagnosis #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Marrow Failure • Chronic ... Myeloproliferative Disease ... diagnosis #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Autoimmunity • Chronic ... Granulomatous lymphocytic ... DDX - Other causes ... : • Nephrotic syndrome
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
changes and may cause ... Malnutrition due to chronic ... disease/malabsorptive ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
+ T-cell count can ... • Leukocyte-lymphocyte ... Photophobia • Lymphocytic ... antibody test) Treatment ... ART to slow HIV disease
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... • Autoimmune diseases ... Adult-onset Still disease ... Treatment: •
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... pneumonia • Chronic ... Lung Abscess Pathophysiology ... Diagnosis: • CBC ... #differential #causes
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