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diagnosis differential cardiorenal causes chloride gitelman hypernatremia hypochloremia hypokalemia management pain sodium workup
Mechanisms of nephron damage in cardiorenal syndrome • Increased renal interstitial pressure • Hypoperfusion • Reduced
Mechanisms of nephron ... in cardiorenal syndrome ... Reduced renal blood flow ... #Mechanisms #pathophysiology ... #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... Implies renal mechanism ... • Euvolemic (Low ... , Cushing syndrome ... #nephrology #sodium
Mechanisms of Pain Mixed - Nociceptive/Neuropathic Nociceptive - Tissue Damage - Visceral - (From organ/cavity lining) Poorly localized,
Mechanisms of Pain ... Well-localized, sharp, short ... regional pain syndrome ... #Neurology #Differential ... #Diagnosis #Algorithm
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Differential Diagnosis Algorithm ... Decreased Intake: • Low ... tubulo-glomerular feedback mechanism ... #Pathophysiology ... #Nephrology #Chloride
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... alkalosis • Normal or low ... Hypocalciuria (spot ... #diagnosis #nephrology ... #management #pathophysiology
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